I earned a B.S. in Biology from the University of Notre Dame, and subsequently completed a Ph.D. in Genetics from Harvard University in the laboratory of Norbert Perrimon, where my graduate work consisted of a molecular and phenotypic analysis of two genes involved in segmentation of the Drosophila embryo. After a postdoctoral interlude in the laboratory of Armen Manoukian at the Ontario Cancer Institute studying the role of heparin sulfate proteoglycans in embryonic development in Drosophila, I returned to the Perrimon lab. I am currently working on projects to determine the functions of miRNAs during development, and to generate new tools for lineage analysis.
I graduated from Penn State with a degree in communications. Before joining the Perrimon Lab, I worked in the Harvard T.H. Chan School of Public Health in Dr. Andrea Baccarelli’s Laboratory of Human Environmental Epigenomics.
Before attending graduate school, I studied plant evolution at UW-Madison and zebrafish developmental genetics at UCSF. For my PhD, I worked with Iswar Hariharan at the UC Berkeley, where I used genetics and cell biology to investigate the molecular mechanisms of tissue growth in Drosophila. In the Perrimon lab, I am studying intercellular communication using the TurboID labeling enzyme and characterizing peptides encoded by small open reading frame genes (smORFs). In addition, I am developing gene-editing methods to better characterize gene function in Drosophila, and I organize a genome engineering journal club at HMS.
I received my Ph.D. from the University of Rochester in the laboratory of Dr. Dirk Bohmann. My doctoral studies were focused towards uncovering novel mechanisms of regulation of Nrf2 signaling and studying their effect on oxidative stress response. In the Perrimon lab I am interested to study how different organs communicate with each other to maintain metabolic homeostasis.
I received my Ph.D. from the University of Texas Health Science Center at Houston. During my graduate studies in Dr. Georg Halder's lab at MD Anderson cancer center, I investigated the role of apical-basal polarity determinants in growth control. Currently, I am interested in using genetic approaches and genomic tools to study the cellular and molecular mechanisms underlying the aging process.
As an undergraduate, I studied developmental biology with Scott Gilbert at Swarthmore College. I then worked as a technician in Doug Emlen's lab at the University of Montana, studying the development of beetle horns, and in 2014 I received my PhD from Harvard University, working in Cassandra Extavour's lab on the embryonic specification of germ cells. In the Perrimon lab, I am studying long-range regulation of germline stem cell proliferation, and I am also interested in developing new tools for manipulating gene expression.
I received my PhD from the University of Minnesota in Dr. Michael O’Connor's lab. I worked on a variety of topics in the O’Connor lab including regulation of developmental timing, metabolic regulation by TGF-beta signaling and cell-type specific RNA tagging. In the Perrimon lab my focus is on the endocrine role of the muscle in regulating metabolism and physiology. In particular I am interested in studying activity induced myokines that signal to distant tissues like the FB and regulates homeostasis.
I obtained my PhD in Denise Montell's group at Department of Biological Chemistry, Johns Hopkins University in 2012. My graduate work used optogenetic and live-cell imaging techniques to study in vivo collective cell migration and tissue morphogenesis. My postdoc research in the Perrimon lab focuses on the mutual recognition and communication between different cell populations and their impacts on organ development and regeneration.
I received my Ph.D from the University of Texas Southwestern Medical Center at Dallas, 2013. During my graduate studies in Dr. Jonathan Terman lab, I explored the cellular and biochemical means through which one of the largest families of axon guidance cues, the Semaphorins, control cell movement. Working on a family of unusual proteins called MICALs, which associated with Semaphorin receptor Plexin, I found that Mical is a novel actin disassembly factor that uses its redox enzymatic activity to oxidize a specific methionine residue of the actin filaments; therefore, disrupts the actin polymerization. Currently, I am interested in using genetic approaches to study the molecular mechanisms of aging.
I received my Ph.D. from the University of Nice-Sophia Antipolis in France in Dr. Stephane Noselli's lab, where I studied the diet-dependent control of oogenesis in Drosophila. I am now combining genetic screens and metabolomics with dietary supplementation approaches to understand how variations in diet rewires the metabolic networks to optimize nutrient utilization during development.
I received my Ph.D at KAIST (Korea Advanced Institute of Science and Techonology) in Prof. Kwang-Wook Choi's lab. In his lab, I studied the regulation of Angiotensin-converting enzyme gene expression during Drosophila development, showing that expression of Angiotensin-converting enzyme is regulated by Mad and Pannier, which regulation is also conserved in human. In addition, I found the interaction between chaperonin function and insulin/TOR signaling in Drosophila.
I obtained my Ph.D. in Biochemistry and Molecular biology from Northwestern University where I studied the mechanism of RNA interference in the laboratory of Dr. Richard Carthew. My research in the Perrimon Lab is focused on understanding the transcriptional regulation of miRNAs and their biological functions in the context of cell growth and survival.
I received my Ph.D in Biological and Biomedical Sciences from Harvard University. I did my thesis work in the lab of Nika Danial where I studied how the liver senses and responds to nutrients like glucose. In the Perrimon lab I am interested in exploring how the gut can sense the environment and regulate systemic metabolism in response to it.
I received my PhD from the University of Queensland, Australia in 2018. In Dr. Sean Millard’s lab, I studied the function and regulation of Drosophila Dscam2 alternative splicing. In the Perrimon Lab, I am interested in understanding the gene regulatory networks that define stem cell states.