Current Lab Members

Rich Binari

Rich Binari, Ph.D.

Lab Manager
I earned a B.S. in Biology from the University of Notre Dame, and subsequently completed a Ph.D. in Genetics from Harvard University in the laboratory of Norbert Perrimon, where my graduate work consisted of a molecular and phenotypic analysis of two genes involved in segmentation of the Drosophila embryo. After a postdoctoral interlude in the laboratory of Armen Manoukian at the Ontario Cancer Institute studying the role of heparin sulfate proteoglycans in embryonic development in Drosophila, I returned to the Perrimon lab. I am currently working on projects to determine the functions of miRNAs during development, and to generate new tools for lineage analysis.
Justin Bosch

Justin Bosch, Ph.D.

Postdoctoral Fellow

Before attending graduate school, I studied plant evolution at UW-Madison and zebrafish developmental genetics at UCSF. For my PhD, I worked with Iswar Hariharan at the UC Berkeley, where I used genetics and cell biology to investigate the molecular mechanisms of tissue growth in Drosophila.

In the Perrimon lab, I am using systematic approaches to study secreted proteins in Drosophila: 1) Mapping the origin and destination of circulating proteins, 2) Identification of peptides encoded from small open reading frame (smORF) genes, and 3) Developing new gene-editing methods to better characterize secreted proteins

To keep scientists up to date on recent genome engineering tools, and give young scientist and opportunity to present their research, I organize a virtual seminar series called Genome Engineering Seminar Series (GESS) at Harvard Medical School (HMS). The meetings are via zoom, free, and open to anyone in the world. I previously organized an in-person genome engineering journal club, which is on hiatus due to Covid.... Read more about Justin Bosch, Ph.D.

Ben Ewen-Campen

Ben Ewen-Campen, Ph.D.

Postdoctoral Fellow
As an undergraduate, I studied developmental biology with Scott Gilbert at Swarthmore College. I then worked as a technician in Doug Emlen's lab at the University of Montana, studying the development of beetle horns, and in 2014 I received my PhD from Harvard University, working in Cassandra Extavour's lab on the embryonic specification of germ cells. In the Perrimon lab, I am studying long-range regulation of germline stem cell proliferation, and I am also interested in developing new tools for manipulating gene expression.

Kerui Huang, Ph.D.

Postdoctoral Fellow

I earned my B.S. in Molecular Genetics from the University of Toronto, where I worked with Dr. Julie Brill on the phosphatidylinositol 4,5-bisphosphate (PIP2) regulation on spermatogenesis using Drosophila. I earned my Ph.D. from Dr. Hua Bai's lab at Iowa State University, where I focused on hepatocyte-like cells (oenocytes) in fruit flies, and their regulatory roles on cardiac health during oxidative stress and aging. In Perrimon's lab, I am specifically interested in how oenocytes regulate whole-body metabolism under normal or stressed conditions.

Patrick     Jouandin, Ph.D.

Patrick Jouandin, Ph.D.

Postdoctoral Fellow
I received my Ph.D. from the University of Nice-Sophia Antipolis in France in Dr. Stephane Noselli's lab, where I studied the diet-dependent control of oogenesis in Drosophila. I am now combining genetic screens and metabolomics with dietary supplementation approaches to understand how variations in diet rewires the metabolic networks to optimize nutrient utilization during development.
Ah-Ram Kim

Ah-Ram Kim, Ph.D.

Postdoctoral Fellow

I received my Ph.D at KAIST (Korea Advanced Institute of Science and Techonology) in Prof. Kwang-Wook Choi's lab. In his lab, I studied the regulation of Angiotensin-converting enzyme gene expression during Drosophila development, showing that expression of Angiotensin-converting enzyme is regulated by Mad and Pannier, which regulation is also conserved in human. In addition, I found the interaction between chaperonin function and insulin/TOR signaling in Drosophila

Liz Lane

Liz Lane, Ph.D.

Postdoctoral Fellow

I received my Ph.D in Biological and Biomedical Sciences from Harvard University. I did my thesis work in the lab of Nika Danial where I studied how the liver senses and responds to nutrients like glucose. In the Perrimon lab I am interested in exploring how the gut can sense the environment and regulate systemic metabolism in response to it.

Joshua Li.jpg

Joshua Li, Ph.D.

Postdoctoral Fellow
I received my PhD from the University of Queensland, Australia in 2018. In Dr. Sean Millard’s lab, I studied the function and regulation of Drosophila Dscam2 alternative splicing.  In the Perrimon Lab, I am interested in understanding the gene regulatory networks that define stem cell states.
Ying Liu

Ying Liu, Ph.D.

Postdoctoral Fellow
I received my Ph.D. in the lab of Dr. Ville Hietakangas at the University of Helsinki in Finland, where I investigated transcriptional regulators involved in nutrient-dependent growth control. In the Perrimon lab, I am interested in exploring the crosstalk between diets and tumor using Drosophila gut tumor model.

Enzo Mameli, Ph.D.

Postdoctoral Fellow

Before graduate school, I studied Biotechnologies and Medical Biotechnologies at the University of Sassari and University of Rome “La Sapienza”, Italy.

I did my PhD studies under the mentorship of Dr. Flaminia Catteruccia, initially at the University of Perugia, Italy, and later on at Harvard T.H. Chan School of Public Health, as part of a visitor exchange program. During this period, I investigated the role of male accessory gland-specific transcription factors regulating reproductive homeostasis and performed mass spectrometry studies to determine the composition of the male “ejaculome” in the malaria mosquito Anopheles gambiae. For a short period after my doctoral studies, I continued my postdoctoral training in the same laboratory following up some research lines generated from my previous work. After this experience I visited Dr. Tonya Colpitts’s lab at Boston University / NEIDL where I familiarized with arboviral infections in insect cell lines and adult Aedes mosquitoes.

In the Perrimon lab I am optimizing the existing Drosophila CRISPR-based wide-genome screening technology for direct application in mosquito cell lines; our principal aim is to use this genetic tool to unravel the complicated interactions between vectors and arboviruses, and decipher how the nature of these relationships shape these viruses epidemiology worldwide.


Jacob Paiano, Ph.D.

Postdoctoral Fellow
I received my PhD in immunology at the University of Pennsylvania, although I completed my thesis at the National Institutes of Health in Bethesda, MD. In the lab of Dr. Andre Nussenzweig, I developed next-generation sequencing methods to study DNA damage and genome integrity during cell division. In the Perrimon Lab, I am interested in studying inter-organ communication networks that coordinate organismal stress responses.

Younshim Park, Ph.D.

Postdoctoral Fellow

I received my Ph.D. from the University of Kansas Medical Center and conducted the research in the laboratory of Dr. Kausik Si located at the Stowers Institute for Medical Research. My doctoral studies were focused on regulatory mechanisms of intron retention during long-term memory formation. In the Perrimon lab I am interested in studying the functional role of protein isoforms in different biological systems.

Afroditi Petsakou

Afroditi Petsakou, Ph.D.

Postdoctoral Fellow
I received my Ph.D. from NYU in the lab of Prof. Justin Blau, where I studied how circadian rhythms control neuronal structural plasticity. For my post-doc in the Perrimon Lab I am investigating the role of enteric neurons in intestinal regeneration.
Pedro Saavedra

Pedro Saavedra, Ph.D.

Postdoctoral Fellow
I received my Ph.D. in Developmental Biology from the University of Cambridge, UK, under the supervision of Dr Peter Lawrence and Dr Isabel Palacios. I used the Drosophila larval epidermis to study the link between planar cell polarity and patterning of tissues during development. Then I had a brief stint in Dr Steven Cohen lab in the IMCB, Singapore, to study how microRNA regulate metabolism and growth. In the Perrimon Lab, my research is focused on muscle degeneration. In particular, I am studying the cellular and molecular mechanisms involved in muscle wasting during cancer-induced cachexia.