Citation:
Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, et al. The twin spot generator for differential Drosophila lineage analysis. Nat Methods. 2009;6 (8) :600-2.
 | 2009_Nat Meth_Griffin.pdf | 508 KB |
| Supplement.pdf | 3.43 MB |
Date Published:
2009 AugAbstract:
In Drosophila melanogaster, widely used mitotic recombination-based strategies generate mosaic flies with positive readout for only one daughter cell after division. To differentially label both daughter cells, we developed the twin spot generator (TSG) technique, which through mitotic recombination generates green and red twin spots that are detectable after the first cell division as single cells. We propose wide applications of TSG to lineage and genetic mosaic studies.
See also: Research Article
