Thermogenesis by THADA
Publication information:
Chatterjee N, Perrimon N. Thermogenesis by THADA.
Dev Cell. 2017;41(1):1–2. PMID: 28399393
Abstract
THADA has been associated with cold adaptation and diabetes in humans, but the cellular and molecular basis of its function has been unknown. Moraru and colleagues (2017) report in this issue of Developmental Cell that it triggers thermogenesis by uncoupling ATP hydrolysis from calcium transport into the endoplasmic reticulum.