Sex determination: co-opted signals determine gender.
Publication information:
Zeidler, Perrimon. Sex determination: co-opted signals determine gender.
Curr Biol. 2000;10(18):R682–4. PMID: 10996811
Abstract
The Drosophila JAK-STAT pathway and its ligand Unpaired are required for a wide range of developmental processes. Recent results have identified Unpaired as an activator of sex-lethal and revealed a new role for the JAK-STAT pathway in sex determination.