@article {843501,
	title = {A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.},
	journal = {Mol Cell Biol},
	volume = {15},
	number = {9},
	year = {1995},
	month = {1995 Sep},
	pages = {5123-30},
	abstract = {
	We have characterized a Drosophila gene that is a highly conserved homolog of the mammalian cyclic AMP (cAMP)-responsive transcription factors CREB and CREM. Uniquely among Drosophila genes characterized to date, it codes for a cAMP-responsive transcriptional activator. An alternatively spliced product of the same gene is a specific antagonist of cAMP-inducible transcription. Analysis of the splicing pattern of the gene suggests that the gene may be the predecessor of the mammalian CREB and CREM genes.

},
	keywords = {Alternative Splicing, Amino Acid Sequence, Animals, Base Sequence, Biological Evolution, Blotting, Northern, Cloning, Molecular, Conserved Sequence, Cyclic AMP Response Element Modulator, Cyclic AMP Response Element-Binding Protein, DNA-Binding Proteins, Drosophila, Drosophila Proteins, Genes, Insect, Head, In Situ Hybridization, Molecular Sequence Data, Protein Binding, Repressor Proteins, Sequence Homology, Amino Acid, Tissue Distribution, Trans-Activators, Transcription, Genetic},
	issn = {0270-7306},
	author = {Yin, J C and Wallach, J S and Wilder, E L and Klingensmith, J and Dang, D and Perrimon, N and Zhou, Y,H. and Tully, T and Quinn, W G}
}
