@article {843491,
	title = {Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.},
	journal = {Cell},
	volume = {84},
	number = {3},
	year = {1996},
	month = {1996 Feb 9},
	pages = {411-9},
	abstract = {
	We have identified a putative Drosophila STAT protein named Marelle that exhibits mutant phenotypes identical to mutations in the Hopscotch/JAK kinase. We show that a reduction in the amount of marelle gene activity suppresses the phenotype associated with a gain-of-function mutation in hopscotch and enhances the phenotype associated with a weak hopscotch mutation. We propose that Hopscotch activates Marelle to regulate transcription of target genes such as the pair rule gene even-skipped. Our results demonstrate the existence of an invertebrate JAK/STAT system.

},
	keywords = {Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, DNA, DNA-Binding Proteins, Drosophila, Drosophila Proteins, Female, Genes, Insect, Janus Kinases, Male, Models, Genetic, Molecular Sequence Data, Mutation, Phenotype, Protein-Tyrosine Kinases, Sequence Homology, Amino Acid, Signal Transduction, Suppression, Genetic, Trans-Activators, Transcription Factors},
	issn = {0092-8674},
	author = {Hou, X S and Melnick, M B and Perrimon, N}
}
