@article {759986,
	title = {Altering the insertional specificity of a Drosophila transposable element.},
	journal = {Proc Natl Acad Sci U S A},
	volume = {89},
	number = {5},
	year = {1992},
	month = {1992 Mar 1},
	pages = {1919-23},
	abstract = {Vectors derived from the Drosophila P element transposon are widely used to make transgenic Drosophila. Insertion of most P-element-derived vectors is nonrandom, but they exhibit a broad specificity of target sites. During experiments to identify cis-acting regulatory elements of the Drosophila segmentation gene engrailed, we identified a fragment of engrailed DNA that, when included within a P-element vector, strikingly alters the specificity of target sites. P-element vectors that contain this fragment of engrailed regulatory DNA insert at a high frequency near genes expressed in stripes.},
	keywords = {Animals, Base Sequence, DNA Transposable Elements, Drosophila melanogaster, Enhancer Elements, Genetic, Gene Expression Regulation, Genes, Molecular Sequence Data, Oligodeoxyribonucleotides, Promoter Regions, Genetic},
	issn = {0027-8424},
	author = {Kassis, J A and Noll, E and VanSickle, E P and Odenwald, W F and Perrimon, N}
}
