HHMI Job Posting - Research Technician (CC30540)

Job Description

The Howard Hughes Medical Institute is seeking a highly motivated technician to join Dr. Norbert Perrimon’s group at Harvard Medical School. The primary focus of this position will be to help produce genome scale libraries of CRISPR-Cas9 reagents and use them to carry out genetic screens.

Principle Responsibilities

- Perform basic Drosophila genetic manipulations, including stock maintenance, expansion and transfer, embryo and adult-timed collections, phenotypic analysis, antibody staining
- Use molecular biology techniques (PCR, gel electrophoresis) to genotype transgenic flies
- Input stock information into laboratory information management system (LIMS)
- Analyze phenotypes generated by RNAi and CRISPR reagents
- Maintain precise records of work
- Work efficiently and cooperatively with a team of researchers
- Opportunity to contribute to research projects

Preferred Qualifications

- Bachelor of Science degree in related field
- Prior practical experience with techniques described above and familiarity with underlying scientific principles
- Ability to draft accurate scientific reports
- Able to apply experience to new techniques and protocols and learn complex tasks with general instruction
- Strong enthusiasm for developing new skills and expertise

Job Location

Boston, Massachusetts, United States

Position Type

Full-Time/Regular

TO APPLY

Please click the position title above to apply through the HHMI website. Please include a cover letter, CV, and three letters of reference. No phone calls please. 

HHMI Job Posting - Bioinformatics Programmer (008079Perrimon2)

Job Description

The Howard Hughes Medical Institute is seeking a highly motivated bioinformatics programmer to join Dr. Norbert Perrimon’s group at Harvard Medical School. We are seeking a candidate who will provide computational support to a dynamic research team by developing and maintaining lab information management systems (LIMs), online research software tools, and related pipelines that facilitate large-scale functional genomic studies. You will work collaboratively with a small team of biologists and programmers in a fast-paced environment.

Principle Responsibilities

- Develop and maintain bioinformatics tools and resources for public use
- Develop and maintain internal LIM (Lab Information Management) system for production tracking
- Collaborate with biologists to assist with research projects, such as data collection and analysis
- Maintain precise records of work
- Work efficiently and cooperatively with a team of researchers
- Opportunity to contribute to research projects

Preferred Qualifications

- Bachelor's degree in Computer Science, or Master's degree in Bioinformatics, Computational Biology, or related field, or equivalent experience
- Proficiency with data structures and algorithms
- Significant experience with one or more, and familiarity with, the coding languages we use (e.g. JavaScript, Python, Perl, Java, PHP)
- Git or other version control experience
- Experience working in a Unix/Linux development environment
- Adept working with MySQL or related databases
- Proven ability to meet deadlines and work cooperatively in a small collaborative team

Job Location

Boston, Massachusetts, United States

Position Type

Full-Time/Regular

TO APPLY

Please click the position title above to apply through the HHMI website. Please include a cover letter, CV, and three letters of reference. No phone calls please. 

HHMI Job Posting - Senior Research Technician (008079-Perrimon)

Job Description

The Howard Hughes Medical Institute is seeking a highly motivated senior-level technician to join Dr. Norbert Perrimon’s group at Harvard Medical School. The successful candidate will be responsible for performing molecular biology, cell culture, protein purification, and/or related techniques as part of an overall research program focused on new technology and resource development (e.g. CRISPR technologies, cell-based assays, protein-based studies). The job requires performing independent work that is coordinated with a larger research team. Although most time will be dedicated to hands-on activities, duties will also include quality assessment (e.g. submission of samples for Sanger sequencing, sequence data analysis) and data entry (e.g. entry of data into a laboratory information management system, preparing of progress updates).

Principle Responsibilities

- Molecular biology, cell culture, protein purification, or related activities
- Quality assessment (e.g. sequence data analysis) related to the above wet-bench activities, including data entry into lab management systems and progress updates
- Development of new workflows, testing of new instruments or technologies, attendance at scientific presentations with a focus on technology, and related technology development or assessment
- Maintain precise records of work
- Work efficiently and cooperatively with a team of researchers
- Opportunity to contribute to research projects

Preferred Qualifications

- S. in related field, Ph.D. preferred
- Experience with cell culture including transfection with plasmids or small RNAs, experience with multiple DNA cloning technologies (Gateway, InFusion, Gibson, etc.)
- Experience with protein purification
- Excellent organizational skills
- Detail oriented
- Ability to work independently and as part of a team
- Ability to communicate clearly on progress made on specific projects
- Ability identify changes in a wet-bench workflow that would improve efficiency and/or quality

Job Location

Boston, Massachusetts, United States

Position Type

Full-Time/Regular

TO APPLY

Please click the position title above to apply through the HHMI website. Please include a cover letter, CV, and three letters of reference. No phone calls please.